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KMID : 0861220150170010031
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Journal of the Korean Society Clinical Neurophysiology
2015 Volume.17 No. 1 p.31 ~ p.34
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A Case of Squamous Cell Lung Cancer Representing as Guillain-Barre Syndrome Associated with Monospecific Anti-GD1b IgG
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Kim Ye-Shin
Kim Seong-Heon
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Abstract
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We report a case with squamous cell lung cancer with concomitant Guillain-Barre syndrome (GBS) as a paraneoplastic syndrome. A 67-year-old patient who was previously diagnosed as metastatic squamous cell lung cancer developed mild symmetrical weakness, paresthesia and sensory ataxia. Nerve conduction study showed sensorimotor polyneuropathy. Analysis of cerebrospinal fluid showed high tilter for monospecific anti-GD1b IgG antibody without onconeuronal antibodies. After treatment with intravenous immunoglobulin, the patient’s symptoms improved.
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KEYWORD
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Guillain-Barre syndrome, Paraneoplastic syndrome, Anti-GD1b antibody
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